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Chloe Stengel Selected Research

Neoplasms (Cancer)

10/2014PIM and AKT kinase inhibitors show synergistic cytotoxicity in acute myeloid leukaemia that is associated with convergence on mTOR and MCL1 pathways.
8/2008IRC-083927 is a new tubulin binder that inhibits growth of human tumor cells resistant to standard tubulin-binding agents.
1/2008STX140 is efficacious in vitro and in vivo in taxane-resistant breast carcinoma cells.
9/2006In vivo efficacy of STX213, a second-generation steroid sulfatase inhibitor, for hormone-dependent breast cancer therapy.

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Chloe Stengel Research Topics

Disease

5Breast Neoplasms (Breast Cancer)
08/2008 - 09/2006
4Neoplasms (Cancer)
10/2014 - 09/2006
1Hypoxia (Hypoxemia)
10/2015
1Uterine Cervical Neoplasms (Cancer of the Cervix)
08/2008

Drug/Important Bio-Agent (IBA)

22- methoxyestradiol- 3,17- O,O- bis(sulfamate)IBA
10/2015 - 01/2008
2Hormones (Hormone)IBA
08/2008 - 09/2006
2Messenger RNA (mRNA)IBA
02/2008 - 09/2006
1Proteins (Proteins, Gene)FDA Link
10/2015
12-ethyloestradiol-bis-sulfamateIBA
10/2015
12-MethoxyestradiolIBA
10/2015
1proto-oncogene proteins pimIBA
10/2014
1Pharmaceutical PreparationsIBA
08/2008
1N- (2- fluoro- 4- (4- (2- (phenoxymethyl)- 1H- imidazol- 4- yl)phenoxy)phenyl)sulfamideIBA
08/2008
1TubulinIBA
08/2008
1Antineoplastic Agents (Antineoplastics)IBA
03/2008
1Docetaxel (Taxotere)FDA Link
01/2008
1taxaneIBA
01/2008
1Paclitaxel (Taxol)FDA LinkGeneric
01/2008
1SulfatasesIBA
09/2006
1estradiol sulfateIBA
09/2006
1Steryl-Sulfatase (Steroid Sulfatase)IBA
09/2006
1EnzymesIBA
09/2006
1STX 213IBA
09/2006
1SteroidsIBA
09/2006

Therapy/Procedure

2Therapeutics
10/2014 - 09/2006
1Injections
09/2006